LaTeX

To create accessible PDF documents with LaTeX, you will need to use additional LaTeX packages. Screen readers require tags and alt text to properly read LaTeX documents and packages will add these to your document. 

To add tags and alt text to the document, add the accessibility package to the preamble:

\usepackage[tagged, highstructure]{accessibility}

• Accessibility package documentation

To make mathematical formulas accessible in your LaTeX document, add the axessibility package to the preamble:

\usepackage{axessibility} 

• Axessibility package documentation

For more information, see:

• Overleaf documentation - An introduction to tagged PDF files: internals and the challenges of accessibility - outlines the concepts and best practices for using Overleaf to make accessible PDFs
• Making Accessible Documents Using LaTeX - an article from the Notices of the American Mathematical Society discussing the difficulties of creating accessible PDFs from LaTeX
• The LaTeX Tagged PDF Project - Documentation from the LaTeX Project
• Instructions to Create a Tagged PDF from a LaTeX File - Rutgers Mathematics Department

Although these packages will help in creating an accessible PDF, be sure and test your document. Creating accessible PDFs from LaTeX is still very much a work in progress.